Drug Guide

Generic Name

Haloprogin

Brand Names Halotex

Classification

Therapeutic: Antifungal

Pharmacological: Allylamine antifungal

FDA Approved Indications

  • Treatment of topical fungal infections such as athlete's foot, ringworm, and candidiasis

Mechanism of Action

Haloprogin inhibits fungal enzymes involved in ergosterol synthesis, disrupting fungal cell membrane formation.

Dosage and Administration

Adult: Apply a thin layer of Halotex to affected area, usually twice daily, for the duration specified by the healthcare provider.

Pediatric: Use as directed by a pediatrician, generally similar to adult dosage.

Geriatric: Use with caution, monitor for hypersensitivity or side effects.

Renal Impairment: No specific adjustments established; caution advised.

Hepatic Impairment: No specific adjustments established; caution advised.

Pharmacokinetics

Absorption: Minimal systemic absorption when used topically.

Distribution: N/A for topical use.

Metabolism: Metabolized locally in skin tissues.

Excretion: Excreted via skin and possibly minor systemic absorption.

Half Life: Not applicable for topical application.

Contraindications

  • Hypersensitivity to haloprogin or other azole antifungals.

Precautions

  • Avoid contact with eyes; discontinue if irritation occurs. Not recommended for use on large open wounds.

Adverse Reactions - Common

  • Skin irritation or dermatitis (Uncommon)

Adverse Reactions - Serious

  • Allergic contact dermatitis or hypersensitivity reactions (Rare)

Drug-Drug Interactions

  • None well documented for topical use.

Drug-Food Interactions

  • None

Drug-Herb Interactions

  • None established.

Nursing Implications

Assessment: Assess site of application for initial skin condition and monitor for adverse reactions.

Diagnoses:

  • Impaired skin integrity related to dermatophyte infection.

Implementation: Apply as prescribed, ensure proper skin cleaning before application.

Evaluation: Monitor lesion improvement and for potential adverse effects.

Patient/Family Teaching

  • Apply medication as directed, usually twice daily.
  • Keep the affected area clean and dry.
  • Report any signs of allergic reaction or severe irritation.
  • Avoid contact with eyes and mucous membranes.

Special Considerations

Black Box Warnings:

  • None.

Genetic Factors: None known.

Lab Test Interference: None.

Overdose Management

Signs/Symptoms: Overuse may lead to localized irritation.

Treatment: Discontinue use, symptomatic treatment as needed.

Storage and Handling

Storage: Store at room temperature, away from heat and moisture.

Stability: Stable under recommended conditions.

🛡️ 5 Critical Medication Safety Tips for Nurses

1

Triple-Check High-Risk Medications

Always have another nurse verify insulin, heparin, warfarin, and chemotherapy drugs. These "high-alert" medications cause the most serious errors. Check concentration, dose calculation, and pump settings twice.

2

Know Look-Alike, Sound-Alike Drugs

Common mix-ups: hydromorphone/morphine, Celebrex/Celexa, Zyprexa/Zyrtec. Always use BOTH generic and brand names, read labels twice, and use barcode scanning when available. One wrong letter can be fatal.

3

Assess Before AND After Giving Meds

Check vitals before cardiac meds, pain levels before analgesics, and blood glucose before insulin. Always reassess within 30 minutes to evaluate effectiveness and watch for adverse reactions.

4

Watch for Drug Interactions

Common dangerous combinations: warfarin + aspirin (bleeding), ACE inhibitors + potassium (hyperkalemia), digoxin + diuretics (toxicity). Always check drug interactions before administering new medications.

5

Educate Your Patients

Teach patients medication names, purposes, major side effects, and what to report. Informed patients catch errors and improve compliance. Always encourage questions - an educated patient is a safer patient.

⚡ Remember: When in doubt, don't give it out! It's always safer to double-check than regret later.

⚠️ Medical Disclaimer

This drug guide is for educational purposes only and is NOT intended for clinical use. Always consult current prescribing information, healthcare providers, and institutional protocols before administering any medication. Do not use this information for patient care decisions.