Home Drug Guide Ammonium Lactate

Drug Guide

Generic Name

Ammonium Lactate

Brand Names Lac-Hydrin

Classification

Therapeutic: Emollient, moisturizer

Pharmacological: Lactic acid derivative, keratolytic, humectant

FDA Approved Indications

Dry, scaly skin conditions such as xerosis, ichthyosis, psoriasis, and eczema

Mechanism of Action

Ammonium lactate acts as a humectant, attracting and retaining moisture in the skin, and as a keratolytic agent, promoting exfoliation of dead skin cells.

Dosage and Administration

Adult: Apply to affected areas once or twice daily or as directed by a healthcare provider.

Pediatric: Use as directed by a healthcare provider; safety and efficacy in children under 2 years have not been established.

Geriatric: Use with caution; monitor for skin irritation.

Renal Impairment: No specific dose adjustment; use with caution as systemic absorption is minimal.

Hepatic Impairment: No specific dose adjustment.

Pharmacokinetics

Absorption: Minimal systemic absorption when applied topically.

Distribution: Local skin effects, not systemic.

Metabolism: Metabolized locally in skin tissues.

Excretion: Excreted via skin; negligible systemic excretion.

Half Life: Not applicable for topical use.

Contraindications

Hypersensitivity to ammonium lactate or its components.

Precautions

Use cautiously on broken or infected skin; avoid ingestion.

Adverse Reactions - Common

Skin irritation, burning, or stinging (Common)

Adverse Reactions - Serious

Allergic contact dermatitis (Rare)

Drug-Drug Interactions

N/A

Drug-Food Interactions

N/A

Drug-Herb Interactions

N/A

Nursing Implications

Assessment: Assess skin condition and tolerance during application.

Diagnoses:

Impaired skin integrity related to skin dryness.

Implementation: Instruct patient on proper application technique; apply to clean, dry skin.

Evaluation: Monitor skin condition for improvement and adverse reactions.

Patient/Family Teaching

Apply as directed; do not overuse.
Avoid applying to broken or infected skin.
Report any signs of irritation or allergic reaction.

Special Considerations

Black Box Warnings: N/A

Genetic Factors: N/A

Lab Test Interference: N/A

Overdose Management

Signs/Symptoms: Localized skin irritation or allergic reaction.

Treatment: Discontinue use; symptomatic treatment for skin irritation.

Storage and Handling

Storage: Store at room temperature, away from moisture and heat.

Stability: Stable under recommended storage conditions.